Actinomycin

Actinomycin D, also known as Dactinomycin, is a potent antineoplastic antibiotic produced via fermentation using Streptomyces species. Widely used in oncology, it plays a crucial role in the treatment of pediatric cancers such as Wilms’ tumor and rhabdomyosarcoma, as well as certain adult cancers. By intercalating DNA and inhibiting RNA synthesis, Actinomycin D effectively halts cancer cell growth. Its production requires advanced fermentation and purification techniques due to its high potency and low yield, making it a high-value, specialty pharmaceutical product.